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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f86fb8593dc578997ebb702339e3b5a687641a8fdd23e0954eb17a4465fed741' 
  AND token = '4zkiaOeCYjRr5oqAbH/1Iz3SgL/SggtMnhrdTKlH8TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}