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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5ca9ca5e70446276c16eb925a574adb2457922d4b8a03a8890be1c477ad1800' 
  AND token = 'L62kuUcXpT27+axzUUP5un0criQK6RyNL+amwiXyYjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}