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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b4c05a9308bf8fcdc809ac0367c3e86a88ef56d60d1b3ad187f67919807ee73' 
  AND token = 'dsZi6wVjdmsbWzuuXZ8CGQqrAZ4ur8do8GZthKGJJPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}