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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '347c49017b3a12160325ebf876149a1eb1ecae99e1bd58927550256c0cab368f' 
  AND token = 'sjnslx1rNsISnbuczOdcWB/RXJBhcshPWxyAIroOy3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}