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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2eac8acfa581aa596217d5368d6c8f0ceebb1a568dd9497d1623d4e4a91165' 
  AND token = '1X7aEzljhtAWFxpbSM+shYT+FydkcKo97uCfyAgITFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}