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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '262b055c99e8da4b60193078a08b5090f5cfe1825329c9b45a5a4720e63f6860' 
  AND token = 'X6qw0F9NTitmzL2EZV30VXBZVOJmPUNnkCM50qra9c4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}