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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4fc886ce509492d48692d5a68af52795b9c04e79ff7428c78e30c4570b0ac42' 
  AND token = 'J6rtdSpbZLdzp1S0FpKhKGs+etUoNS4Kg60N9ERCse4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}