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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a23fb3fb5f8f9e5ba1b40feaa0f6016bee0c12eba93deb17265974507acb809f' 
  AND token = 'dr1mD+tt2zJKaZH+CShwGG6edn5bGO/dMaf7xDn5y7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}