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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6478f586d18ac624f392fc1eb4e95feca46d3041a16e7f1d126f19a052e6160' 
  AND token = 'F7Cz9X9WqdpvqEC3414rdx+2T8LEhptICAkzPhxP4rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}