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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e2543a882553fbda5145c0ac5a2f7fef08f34bd7edb657c1a273a96b00bd105' 
  AND token = '2wzqEk7m15ixCI3XwG3BHyJ2XcGz3p/X+QgYBT3W6oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}