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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15006268cc87329120fe550008aae41f64ab6982b0ccdc820eabb7cd4e38614d' 
  AND token = 'wdziO/HNDYtOpKCShmKtAI3/fXj7tV3tT1bqbp6MHvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}