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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64dbbfe714f2349cd021e4778b27f2f1044ee53c0a2f2328e0a1a6f5b318342c' 
  AND token = 'JyegoV4pg1uWh4eOuN98f7NBpe7qye+eGHaxcCfy5fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}