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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9497f4ec47373ec39613e97fb9d1984554f929524322222f8121f7a2556dcf4' 
  AND token = 'Vw9wwiGNQdAlcMHQYIho6kNvSGx84NsRYIt3QQ404dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}