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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f8a5d8bf95f54ba7d131527b9d10b87c89458caeb42241b10ca84e450add66b' 
  AND token = '//E04oN/tPpdSLqE2sH96x+mS6CSrGUgoNh1n1yJnbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}