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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0478475350020574dfb6ef4feb15dcfbb8d337f879cc064088c244b58ea5ba1' 
  AND token = 'NauaPvhh6m0CgnGBVYiHDmYrWt9dmuGE2j0U8FugyIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}