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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5ce7d6eca43b40d8a2c0093122ca6f0abfa34bd2bb381c49a7129602e11c212' 
  AND token = 'UQnt82Kl3Z6g+gmbcSaxe9wvS3JLShvHxJUmI4X32Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}