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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e61d1ee3229b9ba12f275a290e953073f4f068856bdbcc6db6b660a0e9b5609' 
  AND token = 'C1thuF8M48leo204tMhFFd9VE8tcWFZkDHIrgs6nGOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}