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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eda5871f6461c65035d9b1b2bbb45c1b6fe9387dbac955f38c76abf0259baea2' 
  AND token = 'DGeit3kjVnzF/7XkUiW0x9lokHG+ZeFUZ8Q0V2GI4o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}