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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d7f3f2053368fd543bee0eccadabbe794f6b92b111a1e0c8f3f763a74ea75b3' 
  AND token = 'gn4OM55HN4Ay5QCGXsR3YShaqo4ZD4hWpRh7GLycoKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}