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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59bd5456bc68fe2ed91b9e59d63659ef06d92aec5b681d50d9407ee0b6a0c0f7' 
  AND token = 'WWhDTTzCP5cqAD1H+fEGipB8gwjjg0vDI4Nsq21sfpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}