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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '921fcac7ce51b220894154cad31a0e162117d4c408786339111ec9ce9f18a5b1' 
  AND token = 'FGJ0t+st1tdFoIj/Tkp1On8ID8b69cyE3IAjh7d9Tco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}