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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2cf0eefbd11c94937b8bf7c885095ffc8db09fe202c8f0e04e1646e326f270e' 
  AND token = 'r03bUirQdR9OfVNNcv8UGRXM63xJMwVWjzm8oFJKxII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}