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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee6a74dd769cde545940639ea16683d906dfeaad0f6fec0490165fce01483962' 
  AND token = 'oDVsSawKHTj76M+rjq7MPmHO3Be4wPFSU05VwRywOEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}