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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80eb09bb1bbf788dfabeed8813a5ddc2d63bb07b6a524e0a343d60865d12a7b0' 
  AND token = 'rWqAz5lLPnZRnDtmcAUrZj6JSAJcn3Nw6UUWbQ/lC0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}