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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e91f853516b1f4daa6347937dce4fb7901c97f8ec649ce08a2bca68a9245b7' 
  AND token = 'ULvfoAbKySnb6LDgfeJ0+Z0vl87PCPVo56EZXMDFLY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}