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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '751ede0d8bdc2569cbc76b50bc6280d0800f8ce4ea2dc09592574c9f5f3a6d63' 
  AND token = 'IaKK3+OFBm/4PQU47bzuX2YX53itAeZzDzyNb+fwsZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}