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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4489b88adc11280657c100dc9b3523cb0881245ebe202e3f5d9188fb218c9356' 
  AND token = '95ZYBK+qtOwY8i5/zb6ElZII4FVrHpJPF1D3tqx8V9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}