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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c16d1e7d8821d8a20743d46e4f7365bd5ac35d57340e7849d0b5a254d39ebe00' 
  AND token = 'l9lIZ3BqqV1IHW7TSnIjCABRZ+gqlYbB9602lxRuX2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}