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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d297a2a75e3dd716f6f7cc783baa4e38d706f2a1cb9988d570ed1eda7bc4feb' 
  AND token = 'ETqRzcAEFAZF5W+6TYYFOrzxmSo3Uh+dsUHenZJyOZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}