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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffe1db10a94ab1efc66b1c40b4e2121c80175e318f1144faf2227112f27c4ea4' 
  AND token = 'N3jjU2Ul4ur3KLgDDdo1weuXvyQ88ldHBCgj1vdFCcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}