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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef232ef345beff9b8cb8e5e90c127a1b45ff6521e62d50466a657a3ca0aa1b27' 
  AND token = '7U3zY/HbiYYBhNcjg3F6bC0DnsZ2bxSpJ/CdcZEdOp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}