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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292b0627c5bc8c6bcfd4d77e459812a6114c03ef762772290c532fd7f0f0caf0' 
  AND token = 'rZh3+UXIAeWSx46AEcCKTAgWFuwK4nIAHuQ3ZBdP0BY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}