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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8c555255396b23050388b3b7cb8618aa61188ce51fa7e4dd2ac8d214ca6464f' 
  AND token = 'IHjhdB8q3p4q/vvGmsSSs08E9zS1EQIxW+0CzbnDj5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}