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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b49c43f111c7d433057c22bde48d67c198fc3bd340a67e8d0c0b881a0ec9ccf' 
  AND token = 'SmO9q01B7UEo/r/R8FioNqQbsaRBe4J2aV8BmXwQg5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}