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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42fc2a36a48b3a04e7fc02f7c9ecc41a795da445e4dc85eb35fc227305c58280' 
  AND token = 'JinRwDIFI5q76CZ/Rg2o7Q3nX+S7QbSoMBC08NBsL0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}