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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356a9635090c242a9ec3df1e67e80b8e208f9b31d80d4179c7f6033a3ae799c3' 
  AND token = 'JL5pZED/REBUtt7bN1bfaKiw4b1HPJmfa20FZCGk2Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}