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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c920d9212ccbf333f652fafd05da2ca5e02fa6ce16ab5af2d68d6608e2e9fac' 
  AND token = 'zBY4M75xr3AwiraErpjNjn6Fz0QV+LKBqJv3Oe/cMjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}