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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd612bc405de2a06cb7602d2151b1b631473b17c8bba7c949adaded2d63bafe7' 
  AND token = '4Xy1VkVUBaTCXxKtyUt/suaMrF5MLhbvZ9Ur0LAhX8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}