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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6cd7298ab1dba7ea7e8f34dd6f86c1ad4c943bbeaacd3d363e8461e11e1de18' 
  AND token = 'aQdYlbDVRDLBMY7vvg1xDYvXBWPwwgDpM3oLNa2ZvDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}