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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52bf32c90ede75ec0cb3441bdd4cfe1a18a25ea5e9d6d5f1e76afb417d0bdc21' 
  AND token = '0r5eQrwRs3F2Z+b/+xDhNtX5ncxXIN1+ihL7A5vvQVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}