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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de99ee3f1f03d46401601c7d30bb00db4070fdb129469558b318077ba5037f2' 
  AND token = 'z6wjbyhQhlASW+DXLO6imIuI3aKXtgHTo1DqDQmgL+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}