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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ce5edf472fd70dd63c0fe8ccf3b7cd20ee729f8004344cd503a7125365319ac' 
  AND token = 'plSEtR7FZJ7yzJxESMOppLl+QTwZWP1SalFSJ/1CD3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}