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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1d4faf53408c8ec308e35e85030017ec2c24a842191dfe9f869acef06d6f1c4' 
  AND token = 'YRTz+pMjQa7q9d/MQid8m5U+7lMQCnYGUxt0iQY+RlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}