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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbb0c4421c75e75dc2aca7c43f9d375d7001dabff9ed2171c347dc18ed8111e8' 
  AND token = 'fKLlLEerXDBPL+BCnvwU0jpyfg8OqC0oOc2Zr29RPoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}