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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06ad58c40d285cae0ff0874db490b85c619afa121d37f9e9510d9f1fbcf8c426' 
  AND token = '65Ng8gyp4GPXaXg9WbXumxRSkYIicDb3jMdkCQaQ7+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}