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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ce966433700eb3dd92c6e7f780fc9933799ad9424695c511e950a36bcf16848' 
  AND token = 'gvU+Tg16Am2rLJfC8Ht90aOV8vJQaPtx2XymrfgRhDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}