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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e2a429cb860098701639c30e6fb536205fe59bded3d7699f4847a28bb4a558c' 
  AND token = 'cyRRu/twdVXcISt1w5qhX1r4fgksgaaQXyhIgjTOEJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}