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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5935446990091db3590b412268e9fdf70aee0712f12741ee03341eb4258a7b' 
  AND token = 'npnddnU9dLRfz4bq/1+qEfCYR4IlW/5N5LKQBH8BgzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}