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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fdaf9d9a93949b151c49b94b520c6c507e99f4bf98110cc0e6c7173ac8f6f42' 
  AND token = 'YhMPfOtM0TyCJZYV3rwtbqa+pxamUWd8r1xUkNnMdr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}