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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed3105aa735ea6b592886b7ec3170988ab0d49ceb4491f16c304b53989545af' 
  AND token = 'Uancm3IXLx5XXMY4MLKT8B3+kHXigsMDNWQUKfra9Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}